Today I had my appointment with the Maternal – Fetal specialist, regarding my Anti – E antibody. Dr. J explained everything beautifully and really put my mind at ease. I’ll break it down for you all out there, or at least those who are interested.
Our red blood cells all contain antigens in them the antigens are: D (either negative or positive that determine your Rh factor – positive or negative blood type), C, c, E, and e. These antigens are determined by your genetics – a chromosome from your mother and one from your father. Only two of the antigens, D and C can be treated with medication in terms of it affecting a pregnancy, the rest are only monitored if there is an incompatible antigen with the mother.
So, here is what happened to me. My genetics look like this two separate chromosomes:
D, _ (either C or c here), e | D, _ (either C or c here), e
Mr. Magoo’s looks like this:
D, _ (either C or c here), E | D, _(either C or c here), _ (either E or e here)
Little Magoo’s blood is the same as Mr. Magoo’s, containing the big E antigen. When Little Magoo was born, some of his blood passed through the placenta and mixed with my blood. My little e’s did not like the big E’s invading and quickly formed an antibody to get rid of the big E’s.
Do you follow?
So what does this mean for Baby Magoo #2?
It means that if there is any fetal blood crossing the placenta, my antibodies will rise – this would also indicate that my blood is also crossing the placenta to Baby Magoo and therefore, could cause anemia in the little being growing inside of me. However, there is also the chance that Baby Magoo is not big E positive and his/her genetics contain two little e’s. But, it does mean that the antibodies in my blood will have to be monitored at least once a month and with any possible subsequent pregnancies (IF any!).
The specialist seemed to indicate though, that this was THE problem to have with antigens, if you were to so have a problem, because the risk is so minimal…certainly positive news in my book!
However, if my antibodies were to rise from a 1:8 ratio, where they are now to a 1:16 ratio, the baby would immediately have to be more closely monitored and there could be terrible problems at that point…but the odds of it happening are pretty slim.
Perhaps E and e can co-exist peacefully.
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